Synthesis of 4-methylene-4H-benzo[d][1,3]thiazines via a tandem reaction of 1-(2-alkynylphenyl)ketoximes with Lawesson's reagent.
نویسندگان
چکیده
1-(2-Alkynylphenyl)ketoximes react with Lawesson's reagent catalyzed by InCl(3) and cyanuric chloride leading to 4-methylene-4H-benzo[d][1,3]thiazines in good yields. This tandem reaction proceeds with high efficiency through Beckmann rearrangement, thioamide formation, and intramolecular nucleophilic cyclization.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 34 شماره
صفحات -
تاریخ انتشار 2011